cycle balance natural progesterone creamWhat your doctor may not tell you about the dangers of Depo Provera – DANGER AHEAD

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The Natural Alternative to Provera


Some of the information below is from the article “Provera or The Toxic Drug” according to Dr. Lee and other parts are according to the Physician’s Desk Reference or as noted. Though the cost of depo-provera  can be close to $100 per injection, the actual cost of taking it is much more. It is the physical, emotional, and psychological cost that has no dollar amount. Natural progesterone cream is about $40 for a 3 month supply; including shipping AND it is the natural bio-identical to your own progesterone-manufactured-in-your-body choice.

Depo Provera FAQ list

  1. Adverse reactions to Depo-provera / side effects of depo provera (Dangers of Depo Provera)
  2. Ingredients of Depo-provera and what they do and what they mean
  3. Interesting_tidbits
  4. Warnings about Depo-provera (Dangers of Depo Provera)
  5. Precautions of Depo-Provera (Dangers of Depo Provera)
  6. Weight_loss and weight gain_and Depo-provera
  7. Info from the Provera website

More important than reading the whole article is that I want to list the adverse reactions listed on their site first. This is often what women are looking for on our site. Also, I would like to note that the progesterone creams NOT progestins listed on our site are natural and bio-identical to the progesterone your body would make if it were functioning at a higher, healthier level. You may make wild choices for yourself without worry but there are “little-ones” to consider as well when you are trying to get pregnant or maintain a pregnancy.

Here are the adverse reactions (depo-provera side effects aka What are the real costs involved in taking depo-provera?) says: 

  • See warnings for possible adverse effects on the fetus. (We prefer the name BABY since what you do for TTC is not “fetus dancing” but “baby dancing”.)
  • breakthrough bleeding
  • spotting (visit Reasons For for info about this subject and Beyond Fertility .com which has a large section also.)
  • change in menstrual flow
  • amenorrhea (lack of menstrual period)
  • headaches (migraines)
  • nervousness
  • dizziness
  • edema (water retention)
  • change in weight (increase or decrease)
  • changes in cervical erosion and cervical secretions (this is one I never want to hear about my cervix – EROSION. It is the invitation of cancer but that is not mentioned in that way here.)
  • cholestatic jaundice, including neonatal jaundice (overproduction of bile in the liver)
  • breast tenderness and galactorrhea (fluid from the breast)
  • skin sensitivity reactions consisting of urticaria, pruritus, edema and generalized rash
  • acne, alopecia (hair missing from an area of the body) and hirsutism (hair on face, neck, chest, arms etc for women that is male-like in nature)
  • anaphylactoid reactions and anaphylaxis (Extreme sensitivity to a substance according to
  • mental depression
  • pyrexia (fevers)
  • fatigue
  • insomnia (unable to sleep or fall asleep)

At as I update this page today, they have a sign saying they are updating theirs and are unavailable. The parts from the pfizer website say “ says” before the text.

Depo-provera is made by man. It is not manufactured naturally in the body by God but is made by the Pfizer company. When something is made of inorganic material or the molecular structure is changed, does it make sense that the outcome will also change? Why yes, of course. Enter the – Dangers of Depo Provera.

Here are the ingredients and notes on them in blue. says:

  • medroxyprogesterone acetate – progestin (fake, laboratory progesterone)
  • myristyl gamma picolinium chloride – According to Investigative Ophthalmology when testing this drug on the retina of rabbits – CONCLUSIONS. MGP, the preservative used in Depo-Medrol (and D provera) (Upjohn, Kalamazoo, MI), is highly toxic to the rabbit retina. Read the article and judge for yourself.
  • polyethylene glycol 3350 – we cannot find a definitive answer about this except that it is used as a thickener
  • sodium sulfate anhydrous – reactions are noted if contact is made with the eyes. It does not seem to have a clear explanation in any place I can find but seems to suggest it has a drying effect due to the “anhydrous”.

Ex: Apples provide fiber, vitamins and enzymes, applesauce is changed in the cooking process and the enzymes that help the liver and colon digest and use the nutrients are gone as well as the fiber necessary to sweep the intestines. MORE SO with prescription drugs that begin, as in this case as wild yam, an organic substance and are then altered. At least with applesauce you still get the vitamins.

Here is the first thing on the PDF – says:
Women who use Depo-provera Contraceptive Injection may lose significant mineral density. Bone loss is greater with increasing duration of use and may not be completely reversible.

Does it occur to you that “may lose” and “significant” don’t go well together? I have to ask if they really mean “may” lose or do they mean SIGNIFICANTLY because “may” is significantly overshadowed by the word “significantly”; is it not? They go on to say that Depo-Provera Acetate should be used for long-term (longer than 2 years) birth control, only if other methods  are inadequate. Depo-Provera is also known as medroxyprogesterone acetate. This also should send up warning signs since it is very commonly used for a 2 year period or more and therefore is regularly not a good idea. (Dangers of Depo Provera) says: Depo-Provera gets its name from the fact that it’s provera “deposited”, “injected” into the body rather than oral progesterone or suppositories. Thus the depo part of the name.

Interesting tidbits:
Medroxyprogesterone acetate is used in what is called a “chemical castration” of men who are sex offenders. It is used to lessen their virility and sex drive. According to studies in men also, continued use resulted in loss of bone density and an increase in body fat and long term risk of cardiovascular disease and osteoporosis. says: Medroxyprogesterone stops the secretion of pituitary gonadotropin which keeps the follicular maturation.

Basically, it keeps your body from the benefits of maturing follicles and eggs.

This last paragraph refers to something close to what happens naturally when you are pregnant. BUT decide if you think the following statements on their site continue on the same lines as pregnancy. says:

  • Known or suspected pregnancy or as a diagnostic test for pregnancy.
    Basically don’t use IF you are pregnant or to determine IF you are pregnant. (Miscarriage is sure to follow.)
  • Undiagnosed vaginal bleeding
    Don’t use it if you already have bleeding which has not been identified.
  • Known or suspected malignancy of breast.
    Progesterone is helpful in preventing breast cancer AS IS pregnancy.
  • Liver dysfunction or disease. 
    This is because it is not processed properly by the liver. You will notice from TV commercials that the liver comes up a lot.

Sound familiar?  These are the same for both sexes. Progestins (a name for the group of these chemically altered progesterone compounds) are not the same as the beautiful healthy benefits of your body’s own progesterone.

Here are the warnings (Dangers of Depo Provera) which are even scarier. says:

  • Pregnancy: … in patients with a fertilized defective ova may cause a delay in spontaneous abortion (aka miscarriage)
  • Intrauterine Exposure: … exposure to progestational drugs in the first trimester of pregnancy and genital abnormalities in male and female fetuses. (AKA for those trying to conceive; a BABY) They go on to explain that the male may be “more female” and the female more “male” or as they put it virilization of the external genitalia.
  • Thromboembolic disorders: This has to do with blood disorders, clots, strokes etc.
  • Ocular disorders: Having to do with the eyes especially with complete or partial loss of vision and includes down to something smaller like migraines.
  • Lactation: Drugs have been found in the breast milk of nursing mothers.
  • Multi-dose Use: Special care is necessary to avoid contamination when there are multiple doses in each vial.

Precautions – says:  …fluid retention is to be watched as it can influence conditions such as epilepsy, migraines, asthma, cardiac or renal (kidney) dysfunction. Vaginal bleeding, depression, masking of climacteric (synonymous with menopause)



What follows is the original information from knowing that their site will change as websites do. The rest of the information above came from the website.

Weight loss and depo-provera:
If you are using depo-provera, you may very likely have gained weight; some report 50-60 lbs in a couple years. We can suggest some sites for you to check out: The Diet for a list of healthy supplements or Lose While You Snooze . com and read about their collagen weight loss product to boost your protein and help you lose fat at night in your sleep.

( says: (when this article was first written) Why is this drug prescribed?

Depo-Provera is derived from the female hormone progesterone. You may be given Provera if your menstrual periods have stopped or a female hormones imbalance is causing your uterus to bleed abnormally.

Other forms of medroxyprogesterone, such a Depo-Provera, are used as a contraceptive injection and prescribed in the treatment of endometrial cancer.

Some doctors prescribe Provera to treat endometriosis, menopausal symptoms, premenstrual tension, sexually aggressive behavior in men, and sleep apnea, (temporary failure to breathe while sleeping).

Most important facts about this drug

You should never take Provera during the first 4 months of pregnancy. During this formative period, even a few days of treatment with Provera might put your unborn baby at increased risk for birth defects. If you take Provera and later discover that you were pregnant when you took it, discuss this with your doctor right away.

How should you take his medication?

Provera may be taken with or between meals.

Do not change from one brand to another without consulting your doctor pharmacist.

Your doctor will probably have you take Provera for 5-10 days and then stop; you should have your period within 3-7 days after the last dose.

If you are being treated for lack of regular menstrual periods, your doctor may have you start taking Provera at any time. If you are being treated for abnormal uterine bleeding due to a female-hormone imbalance, your doctor will probably have you start taking Provera on day 16-21 of your menstrual cycle (i.e. 16-21 days after the start of your last period). You should have your period within 3-7 days after the last dose.

What side effects may occur?

Acne, anaphylaxis (life-threatening allergic reaction), blood clot in a vein lungs, or brain, breakthrough bleeding (between menstrual periods), breast tenderness or sudden or excessive flow of milk, cervical erosion or changes in secretions, depression, excessive growth of hair, fever, fluid retention, hair loss, headache, hives, insomnia, itching, lack of menstruation, menstrual flow changes, spotting, nausea, rash, skin discoloration, sleepiness, weight gain or loss, yellowed eyes and skin.

Why should this drug not be prescribed?

Do not take Provera if you are sensitive to it or have ever had an allergic reaction to it.

If you suspect you may have become pregnant, do not take Provera as a test for pregnancy. Doctors once prescribed Provera for this purpose, but no longer do so for 2 reasons:

Quicker, safer pregnancy tests are now available.

If you are in fact pregnant, Provera might injure the baby.

Do not take Provera if you have:

  • Cancer of the breast or genital organs
  • Liver disease or a liver condition
  • A dead fetus still in the uterus
  • Undiagnosed bleeding from the vagina
  • Do not take Provera if you have, or have ever developed blood clots.

Special warnings for this medication

  • Before you start to take Provera, your doctor will give you a complete physical exam, including examination of your breast and pelvic organs. You should also have a cervical smear. (pap test.)
  • Provera may cause some degree of fluid retention. If you have a medical condition that could be made worse by fluid retention – such as epilepsy, migraine,asthma, or a heart or kidney problem – make sure your doctor knows about it.
  • Provera may mask the onset of menopause. In other words, while taking Provera you may continue to experience regular menstrual bleeding even if your menopause has started.
  • Provera may make you depressed, especially if you have suffered from depression in the past. If you become seriously depressed, tell your doctor; you probably stop taking Provera.
  • If you are diabetic, Provera could make your diabetes worse; your doctor will want to watch you closely while you are taking this drug.
  • There is some concern that Provera, like birth controls pills, may increase your risk of blood clots in a vein. If you experience any symptoms that might suggest the onset of such a condition – pain with swelling, warmth, and redness in a leg vein, coughing or shortness of breath, vision problems, migraine, or weakness or numbness in an arm or leg – see your doctor immediately.
    Notice that they say there might be blood clots like with birth control pills, which Pfizer also makes and knows about. Is it worth risking blood clots to use an unnatural, molecularly altered substance?
  • Tell your doctor right away if you lose some or all of your vision or you start seeing double. You may have to stop taking the medication.

Special Information if you are pregnant or breastfeeding:

  • You should not take Provera during pregnancy. If you are pregnant or plan to become pregnant, inform your doctor immediately.
  • Provera appears in breast milk. If you are a new mother, you may need to choose between taking Provera and breastfeeding your baby.

For more info on natural alternatives to Provera read the first four articles under Progesterone Articles


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